Array-based comparative genomic hybridization of circulating esophageal tumor cells
نویسندگان
چکیده
منابع مشابه
Array-based comparative genomic hybridization of circulating esophageal tumor cells.
Esophageal squamous cell carcinoma (ESCC) shows a high frequency of lymphatic and/or systemic metastasis, even when the tumor invades only the submucosa. To investigate the genetic alterations in circulating esophageal tumor cells, we performed array-based comparative genomic hybridization (CGH) analysis of 8 DNA samples of xenografts, which were previously established from the thoracic duct ly...
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Microarray-based comparative genomic hybridization (array CGH) is a revolutionary platform that was recently adopted in the clinical laboratory. This technology was first developed as a research tool for the investigation of genomic alterations in cancer. It allows for a high-resolution evaluation of DNA copy number alterations associated with chromosome abnormalities. Array CGH is based on the...
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Recent developments in DNA microarray technology have enabled a new and highly effective platform for performing comparative genomic hybridization (CGH) measurements. CGH measures anomalies in DNA copy number. Such copy number changes are now thought to play an important role in a number of diseases, particularly cancer and developmental disorders, and may also lead to important insights releva...
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ژورنال
عنوان ژورنال: Oncology Reports
سال: 2006
ISSN: 1021-335X,1791-2431
DOI: 10.3892/or.16.5.1053